Prevalence and Associated Factors of Uterine Rupture During Labor among Women Who Delivered in Debre Markos Hospital North West Ethiopia

Uterine rupture causes high maternal and neonatal mortality in many rural setting in the world. Uterine rupture accounts for about 8% of all maternal deaths. Method and Materials: Facility based cross sectional study design was employed to assess the prevalence and associated factors of uterine rupture.

The data were abstracted from the cases registered during 2010 and 2014 in delivery registers, operating theater registers and patients’ case files of obstetrics ward of Debre Markos Referral Hospital North West Ethiopia. A total of 880 cases were selected by using systematic sampling method.

Result: A sample size of 880 cases was selected after a review of 5-year patients’ records (approx. 16,100 registered delivery cases) from Debre Markos Referral Hospital maternity ward. Among these selected cases, 854 (97.2%) cases were responded for the study. Prevalence of uterine rupture was identified in 81 (9.5%) cases.

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PCOS Patients Needs Much More than Just Pills from Doctors

The discussions by doctors at a local gynecological conference, suggest a strong Apathy towards patients suffering from polycystic ovarian syndrome (PCOS). PCOS has always been an interesting subject to me, so I make it a point to attend and take part in several PCOS related panels in medical conferences.

It is quite evident from all the researches that life style modifications like diet, Exercise and weight reduction play a vital role in the longterm management of PCOS.

As the patients are prone to anxiety and depression, psychological assessment is crucial, along with the physical treatment and dedicated counselors can make a big difference in the outcome of the treatment

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Holistic Approach to Complex Cancer Pain

Cancer pain is a major cause of disability and suffering at the end of life. Cancer pain affects a significant number of patients at the end of life. This case report seeks to highlight some of the complexities associated with managing cancer pain in terminally ill patients.

Nearly 74% of patients with advanced/metastatic cancer will suffer from pain at the end of life. Alarmingly up to 42-51% of these patients will endure suboptimal control of this symptom. It is imperative that patients with difficult pain syndrome are recognised early. This case report spotlights attempts to effectively address complex cancer pain.

Mr S is a 52 year-old gentleman who had enjoyed his independence and mobility despite a long history of hypertension, dyslipidaemia, and ischaemic heart disease. He is a divorcee and stays with his sister. His siblings described him as a cheerful and optimistic person.

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Synthesis and Study of 5[(Phenylsulfonyl)Amino]1,3,4 Thiadiazole 2 Sulfonamide as Potential Anti Pertussis Drug Using Chromatography and Spectroscopy Techniques

Pertussis is a respiratory transmitted disease affecting approximately 23% of the worlds’ population. It is causes by Bordetella Pertussis. The emergence of Multiple Drug Resistant (MDR) Pertussis has focused the attention of the scientific community thought the world on the urgent need for new anti-Pertussis drugs.

In pursuit of this goal, our research efforts are directed toward the discovery of new chemical entities that are effective as anti-Pertussis drugs. During recent years, there have been intense investigations of different classes of 1,3,4- thiadiazole-2-sulfonamide compounds and derivatives such as 5- [(Phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide many of which are known to possess interesting pharmaceutical, biological, biochemical and biomedical properties suchlike anti–microbial, anti– Pertussis and anti–inflammatory activities.

It should be noted that the purity of the synthesized compound was confirmed by High Performance Liquid Chromatography (HPLC) and also Thin–Layer Chromatography (TLC).

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