Tuesday, 4 July 2017

Disabling Bilateral Hip Disease and Femoral Bone Defects Revealing Systemic Sarcoidosis

Bilateral Hip Disease

One involvement in sarcoidosis is rare and often asymptomatic. The small bones of hands and feet are the most common localizations, while skull, knee, rib, pelvic and sternal localizations are rarely reported. Here we report a hip localization.

A 52-year-old woman consulted for acute bilateral coxopathy. Chest radiography objectified bilateral interstitial syndrome with mediastinal lymphadenopathy. The X-ray of the pelvis and both hips showed no abnormalities and CT scan revealed a moth-eaten osteolytic lesion of the left femoral head.

It was associated with inflammatory syndrome and cholestasis. Liver biopsy revealed epithelioid and giant cell granulomas without caseous necrosis. The pathology specimens were interpreted as representing sarcoid.

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