Tuesday, 4 July 2017

Disabling Bilateral Hip Disease and Femoral Bone Defects Revealing Systemic Sarcoidosis

Bilateral Hip Disease

One involvement in sarcoidosis is rare and often asymptomatic. The small bones of hands and feet are the most common localizations, while skull, knee, rib, pelvic and sternal localizations are rarely reported. Here we report a hip localization.

A 52-year-old woman consulted for acute bilateral coxopathy. Chest radiography objectified bilateral interstitial syndrome with mediastinal lymphadenopathy. The X-ray of the pelvis and both hips showed no abnormalities and CT scan revealed a moth-eaten osteolytic lesion of the left femoral head.

It was associated with inflammatory syndrome and cholestasis. Liver biopsy revealed epithelioid and giant cell granulomas without caseous necrosis. The pathology specimens were interpreted as representing sarcoid.

Friday, 30 June 2017

Sickle Cell Trait, Malaria and Sensorineural Hearing Loss–A Case-Control Study from São Tomé and Príncipe

Sickle Cell Trait
Hearing loss is a problem with higher incidence in South Asia, Asia Pacific and sub-Saharan Africa. In these countries there is also associated history of anemia and malaria.

This study aims to identify a putative role of Beta globin mutation - sickle cell trait and HL in São Tomé and Príncipe population. A retrospective case-control study of a convenience sample was collected during Otolaryngologist Humanitarian Missions in São Tomé and Príncipe.

Control group includes individuals with normal hearing in both ears, and the case group has participants presenting bilateral or unilateral HL.

Wednesday, 28 June 2017

Identification of Patient-Perceived Barriers to Communication between Patients and Physicians

Patients and PhysiciansBarriers to full disclosure and communication of complete and accurate health history from patients to their physicians can compromise patient care.

Identification of barriers to communication between patients and their physicians, and assessing communication techniques to overcome putative barriers may improve medical training, quality patient care, and patient experience.

The authors performed a cross-sectional study using a novel questionnaire at an urban, inner-city hospital in Toronto, Ontario between January 1, 2011 and January 1, 2012, in order to evaluate potential barriers to communication.

Friday, 23 June 2017

Human Papilloma Virus (HPV) Vaccines: Scope and Implications

High risk human papilloma virus has often been associated with cancer onset and progression by the virtue of the viral oncogenes.
Human Papilloma Virus

Genital cancers and Oropharyngeal cancers are the two leading carcinomas often induced by HPV infection.

These viral encoded oncogenes are known for their ability to integrate, recombine and interfere with the host cellular genes.

Thursday, 22 June 2017

Determinants of High Fertility among Ever Married Women in Enderta District, Tigray Region, Northern Ethiopia

High Fertility among Ever Married Women
Fertility is one of the major components of population dynamics, which determine the size and structure of a population. According to Ethiopian Demographic and Health Survey 2011 report, the total fertility rate is decreasing from 5.5 children in 2000 to 4.8 in 2011.

However, the rate of decline has been very slow as compared to the developed world. Thus, the objective of this study was to determine the magnitude and factors associated with high fertility among ever married women aged 25-49 years in Northern Ethiopia.

A community based cross-sectional study was conducted on randomly selected 531 subjects in Enderta district using an interviewer administered questionnaire.

Tuesday, 20 June 2017

The Need of Incorporating Pharmacoeconomics in Pharmacy Curriculum of Pakistan

Pharmacoeconomics
The fundamentals of Pharmacoeconomics compare value of a pharmaceutical system over another. Being a sub-discipline of health economics, Pharmacoeconomics appraises the cost and effects of a pharmaceutical product or service hence directs best possible healthcare resource allotment, in a homogeneous and scientifically acceptable approach.

Indeed the use of Pharmacoeconomics in pharmaceutical and medical sciences is a valid and valuable method that is beyond doubt and comparison.

However, there are multiple factors that affect practical application of the Pharmacoeconomical processes in a real time environment.


Monday, 19 June 2017

Left Ventricular Non-Compaction: Mid-myocardial Distribution of Late Gadolinium Enhancement in Compacted Segments

Gadolinium Enhancement
Cardiovascular Magnetic Resonance (CMR) with Late Gadolinium Enhancement (LGE) is a proven method for detecting myocardial fibrosis. Previous CMR studies described the distribution of LGE in patients with LVNC.

however, it still remains unclear. The purpose of the study was to describe the distribution of LGE in patients meeting cardiovascular magnetic resonance criteria for Left Ventricular Non-Compaction (LVNC).

We retrospectively enrolled 15 patients adult patients (11 males and 4 females; mean age, 42 ± 13 years) considered to meet standard CMR criteria for LVNC.