Chronic rhinosinusitis (CRS) is a common
multifactorial upper respiratory disease with a key role of microbes in
worsening of disease and its associated co-morbidities. Further, significant
region specific variation in patient demographics and antibiotic resistance of causative bacteria are reported to pose
difficulty in diagnosis
and treatment.
In India, studies on the etiology and
antibiotic resistance in chronic rhinosinusitis are very meager, especially in
children. The present study aimed to determine the prevalence of common
causative microbes and their antibiotic resistance in children and adolescents
with chronic rhinosinusitis in South Indian population.
Subjects and methods: The present study was
conducted on 89 children and 99 adolescents with chronic rhinosinusitis who
visited MAA ENT Institute, Hyderabad, South India. The study samples were
collected under the nasal endoscopic guidance from the middle meatus at first
visit and sinuses at surgery.
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