Thursday, 12 January 2017

The Benefit and Tolerability of Adjuvant Chemotherapy in Elderly Stage III Colon Cancer Patients

Stage III Colon Cancer
The benefit of adding oxaliplatin to adjuvant fluoropyrimidine chemotherapy in patients >70 years is controversial. This retrospective audit investigated usage, benefit and tolerability of adjuvant chemotherapy for colon cancer in older adults.

Materials and methods: Patients aged >60 years with stage III colon cancer referred for adjuvant chemotherapy between 2010–2012 were identified from a tertiary hospital oncology database. Data were collected on demographics, chemotherapy received, completion rates, toxicities, relapse and survival.

Comparison was made between the older group (age >70 years) and the younger group (age 60-70 years). 95 eligible patients were identified; 50 in the older group (median age 76), 45 in the younger group (median age 66), 56% male, 82% NZ European and 5% Maori.

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