The benefit of adding oxaliplatin to adjuvant
fluoropyrimidine chemotherapy in patients >70 years is controversial. This
retrospective audit investigated usage, benefit and tolerability of adjuvant
chemotherapy for colon cancer in older adults.
Materials and methods: Patients aged >60
years with stage III colon cancer referred for adjuvant chemotherapy between 2010–2012 were
identified from a tertiary hospital oncology database. Data were collected on
demographics, chemotherapy received, completion rates, toxicities, relapse and
survival.
Comparison was made between the older group
(age >70 years) and the younger group (age 60-70 years). 95 eligible
patients were identified; 50 in the older group (median age 76), 45 in the
younger group (median age 66), 56% male, 82% NZ European and 5% Maori.
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