Microparticles
are small (<1.5 μm), anuclear cell vesicles that are released by several
cell types during cell activation and apoptosis and that can be associated by
their surface receptors to their cells of origin (e.g. platelets, endothelial
cells, leukocytes) using flow cytometry.
Initially, it was
believed that microparticles are a kind of cell debris without any distinct
pathological function
However, an increasing number
of publications indicate that MP release is a highly
regulated process and that circulating microparticles indeed have multiple
distinct functions in haemostasis and vascular inflammation
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